MAIN KEGG FILE RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName	#Gene	EntrezGene	Statistics
Cell cycle	9	472 545 64682 9126 10274 5591 8243 10735 8379	C=124;O=9;E=1.45;R=6.20;rawP=1.66e-05;adjP=0.0010
Endometrial cancer	6	6655 324 673 5594 5291 5290	C=52;O=6;E=0.61;R=9.85;rawP=3.23e-05;adjP=0.0010
Hepatitis C	9	6655 8554 673 5610 5290 5600 3661 5594 5291	C=134;O=9;E=1.57;R=5.74;rawP=3.09e-05;adjP=0.0010
Regulation of actin cytoskeleton	11	6655 673 4659 5290 324 23365 3685 200576 5594 5291 9475	C=213;O=11;E=2.49;R=4.41;rawP=4.82e-05;adjP=0.0011
Progesterone-mediated oocyte maturation	7	5600 64682 673 5594 5291 5290 8379	C=86;O=7;E=1.01;R=6.95;rawP=7.01e-05;adjP=0.0013
Focal adhesion	10	6655 673 4659 394 5290 3685 3908 5594 9475 5291	C=200;O=10;E=2.34;R=4.27;rawP=0.0001;adjP=0.0015
RNA degradation	6	9652 54464 246175 29883 23019 1656	C=71;O=6;E=0.83;R=7.22;rawP=0.0002;adjP=0.0023
Lysine degradation	5	54904 55870 80854 10157 29072	C=44;O=5;E=0.52;R=9.70;rawP=0.0002;adjP=0.0023
Non-small cell lung cancer	5	6655 673 5594 5291 5290	C=54;O=5;E=0.63;R=7.91;rawP=0.0004;adjP=0.0040
Acute myeloid leukemia	5	6655 673 5594 5291 5290	C=57;O=5;E=0.67;R=7.49;rawP=0.0005;adjP=0.0041

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).